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Investigation of Pathways for the Low-pH Conformational Transition in Influenza Hemagglutinin

Targeted molecular dynamics simulations were used to study the conformational transition of influenza hemagglutinin (HA) from the native conformation to putative fusogenic or postfusion conformations populated at low pH. Three pathways for this conformational change were considered. Complete dissoci...

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Detalhes bibliográficos
Main Authors: Madhusoodanan, M., Lazaridis, Themis
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302762/
https://ncbi.nlm.nih.gov/pubmed/12609895
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