Multiple regions of RyR1 mediate functional and structural interactions with alpha(1S)-dihydropyridine receptors in skeletal muscle.

Excitation-contraction (e-c) coupling in muscle relies on the interaction between dihydropyridine receptors (DHPRs) and RyRs within Ca(2+) release units (CRUs). In skeletal muscle this interaction is bidirectional: alpha(1S)DHPRs trigger RyR1 (the skeletal form of the ryanodine receptor) to release...

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Detalhes bibliográficos
Main Authors: Protasi, Feliciano, Paolini, Cecilia, Nakai, Junichi, Beam, Kurt G, Franzini-Armstrong, Clara, Allen, Paul D
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302400/
https://ncbi.nlm.nih.gov/pubmed/12496092
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