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KCNE5 induces time- and voltage-dependent modulation of the KCNQ1 current.

The function of the KCNE5 (KCNE1-like) protein has not previously been described. Here we show that KCNE5 induces both a time- and voltage-dependent modulation of the KCNQ1 current. Interaction of the KCNQ1 channel with KCNE5 shifted the voltage activation curve of KCNQ1 by more than 140 mV in the p...

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Autors principals: Angelo, Kamilla, Jespersen, Thomas, Grunnet, Morten, Nielsen, Morten Schak, Klaerke, Dan A, Olesen, Søren-Peter
Format: Artigo
Idioma:Inglês
Publicat: 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302289/
https://ncbi.nlm.nih.gov/pubmed/12324418
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