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Continuum electrostatics fails to describe ion permeation in the gramicidin channel.

We investigate the validity of continuum electrostatics in the gramicidin A channel using a recently determined high-resolution structure. The potential and electric field acting on ions in and around the channel are computed by solving Poisson's equation. These are then used in Brownian dynami...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Edwards, Scott, Corry, Ben, Kuyucak, Serdar, Chung, Shin-Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302233/
https://ncbi.nlm.nih.gov/pubmed/12202360
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