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Site-directed mutagenesis of tyrosine 118 within the central constriction site of the LamB (maltoporin) channel of Escherichia coli. II. Effect on maltose and maltooligosaccharide binding kinetics.

The 3-D structure of the maltooligosaccharide-specific LamB channel of Escherichia coli (also called maltoporin) is known from x-ray crystallography. The central constriction of the channel formed by the external loop 3 is controlled by tyrosine 118. Y118 was replaced by site-directed mutagenesis by...

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Библиографические подробности
Главные авторы: Orlik, Frank, Andersen, Christian, Benz, Roland
Формат: Artigo
Язык:Inglês
Опубликовано: 2002
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302149/
https://ncbi.nlm.nih.gov/pubmed/12080122
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