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Radiolysis of lac repressor by gamma-rays and heavy ions: a two-hit model for protein inactivation.

Upon gamma-ray or argon ion irradiation of the lac repressor protein, its peptide chain is cleaved and the protein loses its lac operator-binding activity, as shown respectively by polyacrylamide gel electrophoresis and retardation gel electrophoresis. We developed phenomenological models that satis...

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Detalhes bibliográficos
Main Authors: Charlier, Michel, Eon, Séverine, Sèche, Edouard, Bouffard, Serge, Culard, Françoise, Spotheim-Maurizot, Mélanie
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302029/
https://ncbi.nlm.nih.gov/pubmed/11964227
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