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Molecular mechanism of H+ conduction in the single-file water chain of the gramicidin channel.

The conduction of protons in the hydrogen-bonded chain of water molecules (or "proton wire") embedded in the lumen of gramicidin A is studied with molecular dynamics free energy simulations. The process may be described as a "hop-and-turn" or Grotthuss mechanism involving the che...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pomès, Régis, Roux, Benoît
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302023/
https://ncbi.nlm.nih.gov/pubmed/11964221
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