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Role of native-state topology in the stabilization of intracellular antibodies.

The role played by the geometric position of each amino acid in the folding process of the immunoglobulin (Ig) variable domain is identified and measured through molecular dynamics simulations of models based on the topology of its native state. This measure allows identifying the parts of the prote...

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Hlavní autoři: Settanni, G, Cattaneo, A, Maritan, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301757/
https://ncbi.nlm.nih.gov/pubmed/11606303
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