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Protonation studies and multivariate curve resolution on oligodeoxynucleotides carrying the mutagenic base 2-aminopurine.

2-Aminopurine (P) is a mutagen causing A.T to G.C transitions in prokaryotic systems. To study the base-pairing schemes between P and cytosine (C) or thymine (T), two self-complementary dodecamers containing P paired with either C or T were synthesized, and their protonation equilibria were studied...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gargallo, R, Vives, M, Tauler, R, Eritja, R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301753/
https://ncbi.nlm.nih.gov/pubmed/11606299
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