Orientation and dynamics of an antimicrobial peptide in the lipid bilayer by solid-state NMR spectroscopy.

The orientation and dynamics of an 18-residue antimicrobial peptide, ovispirin, has been investigated using solid-state NMR spectroscopy. Ovispirin is a cathelicidin-like model peptide (NH(2)-KNLRRIIRKIIHIIKKYG-COOH) with potent, broad-spectrum bactericidal activity. (15)N NMR spectra of oriented ov...

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Bibliographic Details
Main Authors: Yamaguchi, S, Huster, D, Waring, A, Lehrer, R I, Kearney, W, Tack, B F, Hong, M
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301692/
https://ncbi.nlm.nih.gov/pubmed/11566791
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