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Noncontact dipole effects on channel permeation. V. Computed potentials for fluorinated gramicidin.

Experimental and theoretical calculations indicate that the dipole moment of the four Trp side chains in gramicidin A (gA) channels modify channel conductance through long-range electrostatic interactions. Electrostatic ion/side-chain interaction energies along the channel were computed with CHARMM...

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Dettagli Bibliografici
Autori principali: Anderson, D G, Shirts, R B, Cross, T A, Busath, D D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301607/
https://ncbi.nlm.nih.gov/pubmed/11509342
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