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Noncontact dipole effects on channel permeation. II. Trp conformations and dipole potentials in gramicidin A.

The four Trp dipoles in the gramicidin A (gA) channel modulate channel conductance, and their side chain conformations should therefore be important, but the energies of different conformations are unknown. A conformational search for the right-handed helix based on molecular mechanics in vacuo yiel...

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Main Authors: Dorigo, A E, Anderson, D G, Busath, D D
Formato: Artigo
Idioma:Inglês
Publicado: 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300165/
https://ncbi.nlm.nih.gov/pubmed/10096887
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