Interaction of SNX482 with domains III and IV inhibits activation gating of alpha(1E) (Ca(V)2.3) calcium channels.

We have investigated the action of SNX482, a toxin isolated from the venom of the tarantula Hysterocrates gigas, on voltage-dependent calcium channels expressed in tsa-201 cells. Upon application of 200 nM SNX482, R-type alpha(1E) calcium channels underwent rapid and complete inhibition, which was o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Bourinet, E, Stotz, S C, Spaetgens, R L, Dayanithi, G, Lemos, J, Nargeot, J, Zamponi, G W
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301493/
https://ncbi.nlm.nih.gov/pubmed/11423396
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados