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Multiple binding sites for melatonin on Kv1.3.

Melatonin is a small amino acid derivative hormone of the pineal gland. Melatonin quickly and reversibly blocked Kv1.3 channels, the predominant voltage-gated potassium channel in human T-lymphocytes, acting from the extracellular side. The block did not show state or voltage dependence and was asso...

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Main Authors: Varga, Z, Panyi, G, Péter, M, Pieri, C, Csécsei, G, Damjanovich, S, Gáspár, R
Formato: Artigo
Idioma:Inglês
Publicado: 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301322/
https://ncbi.nlm.nih.gov/pubmed/11222291
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