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Effect of pH on the overstretching transition of double-stranded DNA: evidence of force-induced DNA melting.

When a single molecule of double-stranded DNA is stretched beyond its B-form contour length, the measured force shows a highly cooperative overstretching transition. We have investigated the source of this transition by altering helix stability with solution pH. As solution pH was increased from pH...

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Sonraí Bibleagrafaíochta
Main Authors: Williams, M C, Wenner, J R, Rouzina, I, Bloomfield, V A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2001
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301285/
https://ncbi.nlm.nih.gov/pubmed/11159454
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