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Mechanical fatigue in repetitively stretched single molecules of titin.

Relaxed striated muscle cells exhibit mechanical fatigue when exposed to repeated stretch and release cycles. To understand the molecular basis of such mechanical fatigue, single molecules of the giant filamentous protein titin, which is the main determinant of sarcomeric elasticity, were repetitive...

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Auteurs principaux: Kellermayer, M S, Smith, S B, Bustamante, C, Granzier, H L
Format: Artigo
Langue:Inglês
Publié: 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301283/
https://ncbi.nlm.nih.gov/pubmed/11159452
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