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Concurrent binding to multiple ligands: kinetic rates of CD16b for membrane-bound IgG1 and IgG2.

CD16b (FcgammaRIIIb) is the most common receptor for the Fc domain of IgG on leukocytes. The binding of Fc receptors to immunoglobulin triggers a wide array of immune responses. In published assays measuring the reaction of CD16b with isotypes of soluble IgG, the affinity for IgG1 was low and that f...

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Detalhes bibliográficos
Main Authors: Williams, T E, Selvaraj, P, Zhu, C
Formato: Artigo
Idioma:Inglês
Publicado em: 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301077/
https://ncbi.nlm.nih.gov/pubmed/11023891
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