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Inhibition of Ca(2+) sparks by ruthenium red in permeabilized rat ventricular myocytes.

We have compared the effects of the sarcoplasmic reticulum (SR) Ca(2+) release inhibitor, ruthenium red (RR), on single ryanodine receptor (RyR) channels in lipid bilayers, and on Ca(2+) sparks in permeabilized rat ventricular myocytes. Ruthenium red at 5 microM inhibited the open probability (P(o))...

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Bibliografiske detaljer
Main Authors: Lukyanenko, V, Györke, I, Subramanian, S, Smirnov, A, Wiesner, T F, Györke, S
Format: Artigo
Sprog:Inglês
Udgivet: 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301023/
https://ncbi.nlm.nih.gov/pubmed/10968991
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