Dichotomal Effect of the Coumadin Derivative Warfarin on Inflammatory Signal Transduction

Warfarin, a widely prescribed drug for preventing thrombosis, is thought to act solely through inhibition of vitamin K-dependent coagulation factors. Low concentrations of warfarin inhibit interleukin-6 production and phosphorylation of I-κB but not activation of p38 mitogen-activated protein kinase...

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Autores principales: Kater, Arnon P., Peppelenbosch, Maikel P., Brandjes, Dees P. M., Lumbantobing, Mika
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2002
Materias:
Antibodies and Mediators of Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC130100/
https://ncbi.nlm.nih.gov/pubmed/12414784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.9.6.1396-1397.2002
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