Homology modeling and molecular dynamics simulation studies of an inward rectifier potassium channel.

A homology model has been generated for the pore-forming domain of Kir6.2, a component of an ATP-sensitive K channel, based on the x-ray structure of the bacterial channel KcsA. Analysis of the lipid-exposed and pore-lining surfaces of the model reveals them to be compatible with the known features...

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Bibliographic Details
Main Authors: Capener, C E, Shrivastava, I H, Ranatunga, K M, Forrest, L R, Smith, G R, Sansom, M S
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300878/
https://ncbi.nlm.nih.gov/pubmed/10827973
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