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Structural basis for ligand selectivity of heteromeric olfactory cyclic nucleotide-gated channels.

In vertebrate olfactory receptors, cAMP produced by odorants opens cyclic nucleotide-gated (CNG) channels, which allow Ca(2+) entry and depolarization of the cell. These CNG channels are composed of alpha subunits and at least two types of beta subunits that are required for increased cAMP selectivi...

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Bibliografske podrobnosti
Main Authors: Shapiro, M S, Zagotta, W N
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300822/
https://ncbi.nlm.nih.gov/pubmed/10777729
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