Gating of amiloride-sensitive Na(+) channels: subunit-subunit interactions and inhibition by the cystic fibrosis transmembrane conductance regulator.

In search of the structural basis for gating of amiloride-sensitive Na(+) channels, kinetic properties of single homo and heterooligomeric ENaCs formed by the subunits with individual truncated cytoplasmic domains were studied in a cell-free planar lipid bilayer reconstitution system. Our results id...

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Bibliographic Details
Main Authors: Berdiev, B K, Shlyonsky, V G, Karlson, K H, Stanton, B A, Ismailov, I I
Format: Artigo
Language:Inglês
Published: 2000
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300782/
https://ncbi.nlm.nih.gov/pubmed/10733968
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