Polymeric nonelectrolytes to probe pore geometry: application to the alpha-toxin transmembrane channel.

Asymmetrical (one-sided) application of penetrating water-soluble polymers, polyethylene glycols (PEGs), to a well-defined channel formed by Staphylococcus aureus alpha-toxin is shown to probe channel pore geometry in more detail than their symmetrical (two-sided) application. Polymers added to the...

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Bibliographic Details
Main Authors: Merzlyak, P G, Yuldasheva, L N, Rodrigues, C G, Carneiro, C M, Krasilnikov, O V, Bezrukov, S M
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300573/
https://ncbi.nlm.nih.gov/pubmed/10585924
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