Hydrophilicity of a single residue within MscL correlates with increased channel mechanosensitivity.

Mechanosensitive channel large (MscL) encodes the large conductance mechanosensitive channel of the Escherichia coli inner membrane that protects bacteria from lysis upon osmotic shock. To elucidate the molecular mechanism of MscL gating, we have comprehensively substituted Gly(22) with all other co...

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Bibliografiska uppgifter
Huvudupphovsmän: Yoshimura, K, Batiza, A, Schroeder, M, Blount, P, Kung, C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1999
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300477/
https://ncbi.nlm.nih.gov/pubmed/10512816
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