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Physicochemical characterization and purification of cationic lipoplexes.

Cationic lipid-nucleic acid complexes (lipoplexes) consisting of dioleoyltrimethylammoniumpropane (DOTAP) liposomes and plasmid DNA were prepared at various charge ratios (cationic group to nucleotide phosphate), and the excess component was separated from the lipoplex. We measured the stoichiometry...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xu, Y, Hui, S W, Frederik, P, Szoka, F C
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300334/
https://ncbi.nlm.nih.gov/pubmed/10388762
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