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Citrullination: a small change for a protein with great consequences for rheumatoid arthritis

A new autoantibody activity, which is almost 100% specific for rheumatoid arthritis (RA), has been found. The essential part of the B-cell epitope is a modified form of arginine (ie citrulline). The conversion of protein-contained arginine to citrulline is an enzymatic process that is carried out by...

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Bibliografiska uppgifter
Huvudupphovsmän: van Venrooij, Walther J, Pruijn, Ger J M
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC130012/
https://ncbi.nlm.nih.gov/pubmed/11094435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar95
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