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pH-dependent conformational change of gastric mucin leads to sol-gel transition.

We present dynamic light scattering (DLS) and hydrophobic dye-binding data in an effort to elucidate a molecular mechanism for the ability of gastric mucin to form a gel at low pH, which is crucial to the barrier function of gastric mucus. DLS measurements of dilute mucin solutions were not indicati...

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Détails bibliographiques
Auteurs principaux: Cao, X, Bansil, R, Bhaskar, K R, Turner, B S, LaMont, J T, Niu, N, Afdhal, N H
Format: Artigo
Langue:Inglês
Publié: 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300105/
https://ncbi.nlm.nih.gov/pubmed/10049309
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