Single-molecule imaging of RNA polymerase-DNA interactions in real time.

Using total internal reflection fluorescence microscopy, we have directly observed individual interactions of single RNA polymerase molecules with a single molecule of lambda-phage DNA suspended in solution by optical traps. The interactions of RNA polymerase molecules were not homogeneous along DNA...

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Autori principali: Harada, Y, Funatsu, T, Murakami, K, Nonoyama, Y, Ishihama, A, Yanagida, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1999
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1300075/
https://ncbi.nlm.nih.gov/pubmed/9929475
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