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Asymmetrical contributions of subunit pore regions to ion selectivity in an inward rectifier K+ channel.

We have investigated aspects of ion selectivity in K+ channels by functional expression of wild-type and mutant heteromultimeric G protein-coupled inward-rectifier K+ (GIRK) channels in Xenopus oocytes. Within the K+ channel pore (P) region signature sequence, a large number of point mutations in GI...

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Autori principali: Silverman, S K, Lester, H A, Dougherty, D A
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1299807/
https://ncbi.nlm.nih.gov/pubmed/9726934
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