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Distinct Nongenomic Signal Transduction Pathways Controlled by 17β-Estradiol Regulate DNA Synthesis and Cyclin D(1) Gene Transcription in HepG2 Cells

Estrogens induce cell proliferation in target tissues by stimulating progression through the G1 phase of the cell cycle. Activation of cyclin D(1) gene expression is a critical feature of this hormonal action. The existence of rapid/nongenomic estradiol-regulated protein kinase C (PKC-α) and extrace...

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Bibliografske podrobnosti
Main Authors: Marino, Maria, Acconcia, Filippo, Bresciani, Francesco, Weisz, Alessandro, Trentalance, Anna
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC129978/
https://ncbi.nlm.nih.gov/pubmed/12388769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0153
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