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Distinct Nongenomic Signal Transduction Pathways Controlled by 17β-Estradiol Regulate DNA Synthesis and Cyclin D(1) Gene Transcription in HepG2 Cells
Estrogens induce cell proliferation in target tissues by stimulating progression through the G1 phase of the cell cycle. Activation of cyclin D(1) gene expression is a critical feature of this hormonal action. The existence of rapid/nongenomic estradiol-regulated protein kinase C (PKC-α) and extrace...
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Main Authors: | , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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The American Society for Cell Biology
2002
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Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129978/ https://ncbi.nlm.nih.gov/pubmed/12388769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-03-0153 |
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