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DJ-1 has a role in antioxidative stress to prevent cell death
Deletion and point (L166P) mutations of DJ-1 have recently been shown to be responsible for the onset of familial Parkinson's disease (PD, PARK7). The aim of this study was to determine the role of DJ-1 in PD. We first found that DJ-1 eliminated hydrogen peroxide in vitro by oxidizing itself. W...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1298985/ https://ncbi.nlm.nih.gov/pubmed/14749723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400074 |
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