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Gemin proteins are required for efficient assembly of Sm-class ribonucleoproteins
Spinal muscular atrophy (SMA) is a neurodegenerative disease characterized by loss of spinal motor neurons. The gene encoding the survival of motor neurons (SMN) protein is mutated in >95% of SMA cases. SMN is the central component of a large oligomeric complex, including Gemins2–7, that is neces...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1297697/ https://ncbi.nlm.nih.gov/pubmed/16301532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508947102 |
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