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The epithelial Ca(2+) channel TRPV5 is essential for proper osteoclastic bone resorption

Bone remodeling involves the interplay of bone resorption and formation and is accurately controlled to maintain bone mass. Both processes require transcellular Ca(2+) transport, but the molecular mechanisms engaged remain largely elusive. The epithelial Ca(2+) channel TRPV5 is one of the most Ca(2+...

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Autors principals: van der Eerden, Bram C. J., Hoenderop, Joost G. J., de Vries, Teun J., Schoenmaker, Ton, Buurman, Cok J., Uitterlinden, André G., Pols, Huibert A. P., Bindels, René J. M., van Leeuwen, Johannes P. T. M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297662/
https://ncbi.nlm.nih.gov/pubmed/16291808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505789102
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