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Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid

Salmonella enterica relies on a type III secretion system encoded in Salmonella pathogenicity island-2 (SPI-2) to survive and replicate within macrophages at systemic sites during typhoid. SPI-2 virulence is induced upon entry into macrophages, but the mechanisms of SPI-2 gene control in vivo remain...

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Detalhes bibliográficos
Main Authors: Coombes, Brian K., Wickham, Mark E., Lowden, Michael J., Brown, Nat F., Finlay, B. Brett
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297660/
https://ncbi.nlm.nih.gov/pubmed/16301528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505401102
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