A rice-based edible vaccine expressing multiple T cell epitopes induces oral tolerance for inhibition of Th2-mediated IgE responses

Peptide immunotherapy using multiple predominant allergen-specific T cell epitopes is a safe and promising strategy for the control of type I allergy. In this study, we developed transgenic rice plants expressing mouse dominant T cell epitope peptides of Cry j I and Cry j II allergens of Japanese ce...

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Autors principals: Takagi, Hidenori, Hiroi, Takachika, Yang, Lijun, Tada, Yoshifumi, Yuki, Yoshikazu, Takamura, Kaoru, Ishimitsu, Ryotaro, Kawauchi, Hideyuki, Kiyono, Hiroshi, Takaiwa, Fumio
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2005
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297655/
https://ncbi.nlm.nih.gov/pubmed/16278301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0503428102
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