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Recombinant human activated protein C resets thrombin generation in patients with severe sepsis – a case control study

INTRODUCTION: Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate...

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Detalhes bibliográficos
Main Authors: de Pont, Anne-Cornélie JM, Bakhtiari, Kamran, Hutten, Barbara A, de Jonge, Evert, Vroom, Margreeth B, Meijers, Joost CM, Büller, Harry R, Levi, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297612/
https://ncbi.nlm.nih.gov/pubmed/16277710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc3774
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