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Recombinant human activated protein C resets thrombin generation in patients with severe sepsis – a case control study

INTRODUCTION: Recombinant human activated protein C (rhAPC) is the first drug for which a reduction of mortality in severe sepsis has been demonstrated. However, the mechanism by which this reduction in mortality is achieved is still not clearly defined. The aim of the present study was to evaluate...

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Bibliografski detalji
Glavni autori: de Pont, Anne-Cornélie JM, Bakhtiari, Kamran, Hutten, Barbara A, de Jonge, Evert, Vroom, Margreeth B, Meijers, Joost CM, Büller, Harry R, Levi, Marcel
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297612/
https://ncbi.nlm.nih.gov/pubmed/16277710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc3774
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