Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats

Tetrathiomolybdate (TM), a drug developed for Wilson's disease, produces an anti-angiogenic and anti-inflammatory effect by reducing systemic copper levels. TM therapy has proved effective in inhibiting the growth of tumors in animal tumor models and in cancer patients. We have hypothesized tha...

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Autors principals: Omoto, Atsushi, Kawahito, Yutaka, Prudovsky, Igor, Tubouchi, Yasunori, Kimura, Mizuho, Ishino, Hidetaka, Wada, Makoto, Yoshida, Makie, Kohno, Masataka, Yoshimura, Rikio, Yoshikawa, Toshikazu, Sano, Hajime
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2005
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297562/
https://ncbi.nlm.nih.gov/pubmed/16277669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar1801
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