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Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays

Nephrophilic autoantibodies dominate the seroprofile in lupus, but their fine specificities remain ill defined. We constructed a multiplexed proteome microarray bearing about 30 antigens known to be expressed in the glomerular milieu and used it to study serum autoantibodies in lupus. Compared with...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhen, Quan Li, Xie, Chun, Wu, Tianfu, Mackay, Meggan, Aranow, Cynthia, Putterman, Chaim, Mohan, Chandra
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1297234/
https://ncbi.nlm.nih.gov/pubmed/16322790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23587
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