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An endocrine pathway in the prostate, ERβ, AR, 5α-androstane-3β,17β-diol, and CYP7B1, regulates prostate growth

Epithelial proliferation of the ventral prostate in rodents peaks between 2 and 4 weeks of age, and by week 8, proliferating cells are rare. We have used ERβ(−/−) and CYP7B1(−/−) mice to investigate the role of ERβ and one of its ligands, 5α-androstane-3β,17β-diol (3βAdiol), in growth of the ventral...

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Bibliografische gegevens
Hoofdauteurs: Weihua, Zhang, Lathe, Richard, Warner, Margaret, Gustafsson, Jan-Åke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129718/
https://ncbi.nlm.nih.gov/pubmed/12370428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162477299
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