Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: A relic of early life?

In most Gram-positive bacteria, serine-46-phosphorylated HPr (P-Ser-HPr) controls the expression of numerous catabolic genes (≈10% of their genome) by acting as catabolite corepressor. HPr kinase/phosphorylase (HprK/P), the bifunctional sensor enzyme for catabolite repression, phosphorylates HPr, a...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Mijakovic, Ivan, Poncet, Sandrine, Galinier, Anne, Monedero, Vicente, Fieulaine, Sonia, Janin, Joël, Nessler, Sylvie, Marquez, José Antonio, Scheffzek, Klaus, Hasenbein, Sonja, Hengstenberg, Wolfgang, Deutscher, Josef
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12359880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212410399
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