X-ray structure of a bifunctional protein kinase in complex with its protein substrate HPr

HPr kinase/phosphorylase (HprK/P) controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by Gram-positive bacteria. It catalyzes both the ATP-dependent phosphorylation of Ser-46 of HPr and its dephosphorylation by phosphorolysis. The latt...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Fieulaine, Sonia, Morera, Solange, Poncet, Sandrine, Mijakovic, Ivan, Galinier, Anne, Janin, Joël, Deutscher, Josef, Nessler, Sylvie
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 2002
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC129691/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12359875/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.192368699
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