Essential myosin light chain as a target for caspase-3 in failing myocardium

Programmed cell death involves the activation of caspase proteases that can mediate the cleavage of vital cytoskeletal proteins. We have recently reported that, in failing cardiac myocytes, caspase-3 activation is associated with a reduction in contractile performance. In this study we used a modifi...

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Hlavní autoři: Moretti, Alessandra, Weig, Hans-Jörg, Ott, Thomas, Seyfarth, Melchior, Holthoff, Hans-Peter, Grewe, Diana, Gillitzer, Angelika, Bott-Flügel, Lorenz, Schömig, Albert, Ungerer, Martin, Laugwitz, Karl-Ludwig
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC129359/
https://ncbi.nlm.nih.gov/pubmed/12186978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182373099
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