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Protein–DNA computation by stochastic assembly cascade

The assembly of RecA on single-stranded DNA is measured and interpreted as a stochastic finite-state machine that is able to discriminate fine differences between sequences, a basic computational operation. RecA filaments efficiently scan DNA sequence through a cascade of random nucleation and disas...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bar-Ziv, Roy, Tlusty, Tsvi, Libchaber, Albert
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC129313/
https://ncbi.nlm.nih.gov/pubmed/12186973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.162369099
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