Isolation and Characterization of New Thiamine-Deregulated Mutants of Bacillus subtilis

In bacteria, thiamine pyrophosphate (TPP) is an essential cofactor that is synthesized de novo. Thiamine, however, is not an intermediate in the biosynthetic pathway but is salvaged from the environment and phosphorylated to TPP. We have isolated and characterized new mutants of Bacillus subtilis th...

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Bibliographic Details
Main Authors: Schyns, Ghislain, Potot, Sébastien, Geng, Yi, Barbosa, Teresa M., Henriques, Adriano, Perkins, John B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291275/
https://ncbi.nlm.nih.gov/pubmed/16291685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.187.23.8127-8136.2005
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