Loss of SOD1 and LYS7 Sensitizes Saccharomyces cerevisiae to Hydroxyurea and DNA Damage Agents and Downregulates MEC1 Pathway Effectors

Aerobic metabolism produces reactive oxygen species, including superoxide anions, which cause DNA damage unless removed by scavengers such as superoxide dismutases. We show that loss of the Cu,Zn-dependent superoxide dismutase, SOD1, or its copper chaperone, LYS7, confers oxygen-dependent sensitivit...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Carter, Carole D., Kitchen, Lauren E., Au, Wei-Chun, Babic, Christopher M., Basrai, Munira A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1291217/
https://ncbi.nlm.nih.gov/pubmed/16287844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.23.10273-10285.2005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados