Ras Mutation Impairs Epithelial Barrier Function to a Wide Range of Nonelectrolytes

Although ras mutations have been shown to affect epithelial architecture and polarity, their role in altering tight junctions remains unclear. Transfection of a valine-12 mutated ras construct into LLC-PK(1) renal epithelia produces leakiness of tight junctions to certain types of solutes. Transepit...

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Hauptverfasser: Mullin, James M., Leatherman, James M., Valenzano, Mary Carmen, Huerta, Erika Rendon, Verrechio, Jon, Smith, David M., Snetselaar, Karen, Liu, Mantao, Francis, Mary Kay, Sell, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2005
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289400/
https://ncbi.nlm.nih.gov/pubmed/16176977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-04-0294
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