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The Oxysterol-binding Protein Homologue ORP1L Interacts with Rab7 and Alters Functional Properties of Late Endocytic Compartments

ORP1L is a member of the human oxysterol-binding protein (OSBP) family. ORP1L localizes to late endosomes (LEs)/lysosomes, colocalizing with the GTPases Rab7 and Rab9 and lysosome-associated membrane protein-1. We demonstrate that ORP1L interacts physically with Rab7, preferentially with its GTP-bou...

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Detalhes bibliográficos
Main Authors: Johansson, Marie, Lehto, Markku, Tanhuanpää, Kimmo, Cover, Timothy L., Olkkonen, Vesa M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289395/
https://ncbi.nlm.nih.gov/pubmed/16176980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E05-03-0189
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