Silencing of human T-cell leukemia virus type I gene transcription by epigenetic mechanisms

BACKGROUND: Human T-cell leukemia virus type I (HTLV-I) causes adult T-cell leukemia (ATL) after a long latent period. Among accessory genes encoded by HTLV-I, the tax gene is thought to play a central role in oncogenesis. However, Tax expression is disrupted by several mechanims including genetic c...

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Main Authors: Taniguchi, Yuko, Nosaka, Kisato, Yasunaga, Jun-ichirou, Maeda, Michiyuki, Mueller, Nancy, Okayama, Akihiko, Matsuoka, Masao
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289293/
https://ncbi.nlm.nih.gov/pubmed/16242045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-2-64
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