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CONJUGATED LINOLEIC ACID PROMOTES HUMAN ADIPOCYTE INSULIN RESISTANCE THROUGH NFκB-DEPENDENT CYTOKINE PRODUCTION

We previously demonstrated that trans-10, cis-12 conjugated linoleic acid (CLA) reduced the triglyceride (TG) content of human adipocytes by activating mitogen-activated protein kinase kinase/extracellular signal-related kinase (MEK/ERK) signaling via interleukins-6 (IL-6) and 8 (IL-8). However, the...

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Detalhes bibliográficos
Main Authors: Chung1, Soonkyu, Brown2, J. Mark, Provo1, J. Nathan, Hopkins1, Robin, McIntosh1, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1289266/
https://ncbi.nlm.nih.gov/pubmed/16155293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M508159200
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