Cross-reactive influenza virus–specific CD8+ T cells contribute to lymphoproliferation in Epstein-Barr virus–associated infectious mononucleosis

The marked proliferation of activated CD8(+) T cells is pathognomonic of EBV-associated infectious mononucleosis (IM), common in young adults. Since the diversity and size of the memory CD8(+) T cell population increase with age, we questioned whether IM was mediated by the reactivation of memory CD...

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Main Authors: Clute, Shalyn C., Watkin, Levi B., Cornberg, Markus, Naumov, Yuri N., Sullivan, John L., Luzuriaga, Katherine, Welsh, Raymond M., Selin, Liisa K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2005
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1288832/
https://ncbi.nlm.nih.gov/pubmed/16308574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI25078
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